Arthritis Pain Treatment

Utah Celebrates Arthritis Awareness Month In May

2009-05-15 08:54

Nearly 40% of Utahns over age 65 who suffered a traumatic brain injury in a fall in 2006 also had arthritis. In 2005 it was just 29%. And the problem will only worsen as today’s baby boomers age.

The Utah Department of Health (UDOH) Violence and Injury Prevention (VIPP) and Arthritis (UAP) programs are joining forces to celebrate Arthritis Awareness Month in May. Their goal is to better understand if people with arthritis are more prone to falling and if so, why.

Computer Use Problems Common in Arthritis Patients

2009-05-11 13:29

Nancy Baker, Sc.D., of the University of Pittsburgh, and colleagues report more than 75% of patients with rheumatoid arthritis (RA), osteoarthritis (OA), or fibromyalgia report problems with discomfort when using a computer. The report was published in the May issue of Arthritis Care & Research.

Arthritis patients often choose less physically demanding jobs, such as administrative or clerical positions. These days those jobs are very likely to involve computer time.

Aging Population Faces High Rates Of Arthritis

2009-05-07 12:37

When asked if they are disabled, more Americans who say yes report ‘arthritis or rheumatism’ as the most common culprit. A Centers for Disease Control and Prevention (CDC) study found that, by the year 2030, the number of disabled Americans will skyrocket 40 percent, affecting more than 67 million people.

FDA Approves New Drug For Immune-Related Arthritis Treatment

2009-04-27 07:24

The U.S. Food and Drug Administration today approved Simponi (golimumab), a monthly treatment for adults with moderate-to-severe rheumatoid arthritis, active psoriatic arthritis, and active ankylosing spondylitis.

All three conditions are chronic disorders in which the immune system attacks multiple joints, causing stiffness, pain, and restricted motion.

Assessing Surgical Procedure For Regenerating Cartilage In Damaged Knee Joints

2009-04-15 06:21

Rush University Medical Center is testing a new procedure for regenerating damaged articular cartilage in the knee joint to relieve the pain of osteoarthritis. Rush is the only center in Illinois participating in the CAIS Phase III clinical trial.

Exposure To Traffic Pollution Leads To Rheumatoid Arthritis Risk

2009-04-03 11:50

Using data from the Nurses’ Health Study, researchers from Brigham and Women’s Hospital (BWH) and colleagues found that exposure to traffic pollution may increase the risk of developing rheumatoid arthritis (RA). These findings appear in an advanced online publication of Environmental Health Perspectives.

Fear Of Arthritis Pain May Keep Heart Disease Patients Inactive

2009-03-27 08:30

A new nationwide Centers for Disease Control and Prevention (CDC) study shows that 56.6 percent of Kansas adults with heart disease also have arthritis, a painful condition that may be a barrier to physical activity—an essential strategy for people trying to manage and control their heart disease.

Arthritis Pain Keeps Utahns With Heart Disease Inactive

2009-03-18 11:46

A new Centers for Disease Control and Prevention (CDC) study shows that 55 percent of Utah adults with heart disease also have arthritis, a painful condition that may be a barrier to physical activity—an essential strategy for people trying to manage and control their heart disease.

Arthritis Pain May Keep People With Heart Disease Physically Inactive

2009-03-02 13:37

Arthritis may create an additional barrier to using physical activity to help people manage their heart disease, according to a study by the Centers for Disease Control and Prevention. Adults with both heart disease and arthritis are significantly more likely to be physically inactive than those with heart disease alone, the study said.

The study in the Morbidity and Mortality Weekly Report (MMWR), found that arthritis is common among those having heart disease. Approximately 57 percent of adults with heart disease have arthritis.

Arthritis Hinders Physical Activity In Heart Disease Adults

2009-02-26 15:09

Arthritis affects more than half of adults with heart disease and appears to be a substantial barrier to utilizing physical activity to help manage their condition, according to a new Morbidity and Mortality Weekly Report (MMWR) study released today by the Centers for Disease Control and Prevention (CDC).

According to the Arthritis Foundation, the study underscores the importance of physical activity in effective management for adults with both arthritis and heart disease.

Gout Sufferers Now Have Uloric for Treatment

2009-02-15 19:46

Gout is a painful joint disease affecting about five million people in the United States. Gout is a form of arthritis that is caused by a build-up of uric acid in the blood.

On Friday, the Food and Drug Administration approved Uloric (febuxostat) giving gout sufferers a new drug to treat their disease. It is the first new treatment for gout in over 40 years. The drug is produced by Takeda Pharmaceuticals North America, Inc.

Uloric works by blocking the enzyme xanthine oxidase and therefore reducing levels of blood uric acid. It is a once-daily drug.

New Guidelines for Treatment of Knee Osteoarthritis

2009-02-04 11:44

The American Academy of Orthopaedic Surgeons (AAOS) released its recommendations in December 2008 for "best" practice guidelines. In looking at the commonly used treatments for osteoarthritis (OA), they underscored that many lack support from scientific evidence.

The AAOS guideline targets treatment for patients with OA of the knee whose disease has not progressed to the point of needing joint replacement surgery. It offers 22 treatment recommendations. The guideline is aimed at primary care physicians as well as orthopedic surgeons.

Study Shows Rheumatoid Arthritis Responding To Gene Therapy

2009-02-02 09:26

A study that delivers the first clinical evidence that gene therapy can reduce the symptoms of patients with rheumatoid arthritis appeared in the February issue of Human Gene Therapy. The authors of the study, which was carried out in 1997 and 1998 under the direction of Dr. Peter Wehling, Düsseldorf, Germany, describe the findings of a study involving two patients with severe rheumatoid arthritis.

No Proven Role For Diet In Treating Rheumatoid Arthritis

2009-01-29 10:30

A new review finds no definitive connection between diet and rheumatoid arthritis (RA), a disease in which the body’s immune system attacks the lining of the joints.

As an individual’s rheumatoid arthritis progresses, his or her joints can become swollen and stiff, reducing mobility. While treatments are available to relieve some of these symptoms, no cure exists.

Novel Drugs May Be Hope For Rheumatoid Arthritis Treatment

2009-01-13 17:04

Methotrexate (MTX), a folate antagonist that blocks folic acid activity, is the most widely used disease-modifying antirheumatic drug (DMARD) for rheumatoid arthritis. It enters the cell via several pathways, one of which involves folate receptor β (FRβ), which is highly specific for cells present in the joints of patients with rheumatoid arthritis (RA). During the last two decades, a second generation of folate antagonists has been designed to address some of the limitations of MTX, which include adverse side effects and resistance.

New Clinical Practice Guideline For Knee Osteoarthritis Issued

2008-12-12 07:26

The American Academy of Orthopaedic Surgeons (AAOS) has approved and released an evidence-based clinical practice guideline on "Treatment of Osteoarthritis of the Knee". These guidelines were explicitly developed to include only treatments which are less invasive than knee replacement surgery. While a wide range of treatment options are available, they should always be tailored to individual patients after discussions with their physicians.

The Guidelines and Evidence Report recommends:

CEL-SCI's Rheumatoid Arthritis Vaccine Benefits Last Long

2008-11-15 00:23

CEL-SCI Corporation presented new rheumatoid arthritis data at the 6th annual GTCbio Vaccine Conference in Vienna, Va. The data, presented by Dr. Daniel Zimmerman, Senior Vice President of Research, Cellular Immunology of CEL-SCI, indicate that CEL-SCI's rheumatoid arthritis treatment vaccine CEL-2000 prevents or retards the permanent tissue damage caused by rheumatoid arthritis. The long term results obtained with CEL-2000 vaccine, for the rheumatoid arthritis, were in line with those seen with Enbrel, a leading treatment for people with rheumatoid arthritis.

Antiangiogenic Role Of 2ME2 Demonstrated In Rheumatoid Arthritis Models

2008-11-03 23:41

EntreMed, Inc. (Nasdaq: ENMD), a clinical-stage pharmaceutical company developing therapeutics for the treatment of cancer and inflammatory diseases, today announced the publication of preclinical results for 2ME2 (Panzem or 2-methoxyestradiol) in rheumatoid arthritis (RA). The results of the study, conducted by EntreMed collaborator, Dr. Ernest Brahn, Professor of Medicine, Rheumatology Program Director, David Geffen School of Medicine at UCLA, were published in the November 2008 issue of the Journal of Rheumatology (Brahn E, Banquerigo ML, Lee JK, Park EJ, Fogler WE, and Plum SM.

ACTEMRA Inhibited Progression Of Joint Damage In RA Patients Demonstrated

2008-10-29 07:40

One-year data from a two-year Phase III study demonstrated that ACTEMRA (tocilizumab) significantly inhibited the progression of structural joint damage in patients with rheumatoid arthritis (RA). Late-breaking results from the LITHE study will be featured as an oral presentation during the American College of Rheumatology (ACR) Annual Scientific Meeting (October 24-28) in San Francisco. Fourteen additional abstracts, which evaluate ACTEMRA, a novel interleukin-6 (IL-6) receptor inhibitor, in patients with moderately to severely active RA, will also be presented during the meeting.

ACTEMRA Significantly Reduced Signs, Symptoms Of Rheumatoid Arthritis

2008-10-28 00:49

Data from two Phase III studies showed that patients who suffer from the debilitating and painful effects of rheumatoid arthritis (RA) achieved significant improvements in signs and symptoms when treated with ACTEMRA (tocilizumab) alone or in combination with methotrexate compared with methotrexate alone.

Discovery Yields Potential Gout Treatment

2008-10-27 13:41

A new approach to treating gout -- a debilitating form of arthritis -- can normalize levels of uric acid in the blood within hours in patients who have failed to respond to any other treatments, and in some patients, eliminate the painful, needle-like crystals of uric acid that clump around fingers, toes and other joints.

Details of the use of the drug, pegloticase, among 212 patients with severe gout enrolled in two, phase III clinical trials, were released today at the annual meeting of the American College of Rheumatology.

Mayo Research Says Rheumatoid Arthritis Rising Among Women

2008-10-27 05:37

After four decades on the decline, rheumatoid arthritis is on the upswing among women in the United States. That's the finding presented by Mayo Clinic investigators at the annual meeting of the American College of Rheumatology/Association of Rheumatology Health Professionals in San Francisco.

"This is a significant finding and an indicator that more research needs to be done to better understand the causes and treatment of this devastating disease," says Sherine Gabriel, M.D., Mayo Clinic rheumatologist and lead investigator on the study.

Health and Wellness: 

Treatment of psoriatic arthritis gets international guidelines

2008-10-27 05:17

Rheumatologists, dermatologists, and patient advocates have come together to publish the first-ever international guidelines for the treatment of psoriatic arthritis, a disease that mainly affects people who have psoriasis but also some people without it.

Health and Wellness: 

New osteoarthritis study shows: most treatments don't work

2008-10-23 14:27

Meta-analysis calls into question the premises underlying classic osteoarthritis treatment guidelines.

Berlin, October 23, 2008. Despite the billions of euros spent on osteoarthritis treatments in Germany, the effectiveness of those treatments remains highly controversial among experts. According to the findings of a large-scale study presented today by Carsten Moser and Peter Wehling of Düsseldorf at the Orthopedics and Trauma Surgery Congress in Berlin, the largest German orthopedics conference, some therapies have now been shown to be ineffective while others are downright risky.

UK Researchers Scanning Arthritis Study

2008-10-08 03:23

Leeds researchers are among the first in the country to use new state-of-the art imaging equipment in a bid to improve the diagnosis and monitoring of patients with a common form of inflammatory arthritis.

A team from the Leeds Institute of Molecular Medicine at the University of Leeds hope to demonstrate the effectiveness of two novel imaging techniques using a specially adapted MRI scanner.

Six New Genetic Indicators For Rheumatoid Arthritis

2008-10-08 03:14

Researchers from Brigham and Women's Hospital (BWH) and colleagues have uncovered specific locations on chromosomes (loci) linked to rheumatoid arthritis (RA), a progressive autoimmune disease that attacks the joints and other organs. Variations in the genetic sequence at these locations imply a risk of developing RA.

Occupational Therapy Gets People With Osteoarthritis Moving

2008-10-02 02:41

Physical activity is the cornerstone of any healthy lifestyle – and especially for people with osteoarthritis as exercise helps maintain good joint health, manage their symptoms, and prevent functional decline. Osteoarthritis, however, often makes physical activity, such as exercise, and even performing daily activities, a challenge.